Guardians of the Past: Safeguarding a Nation\u27s Heritage through Manuscripts and Rare Collections

Preserving a nation\u27s traditional and cultural heritage is imperative to transcending generations. Manuscripts and rare collections serve as invaluable windows into the past, allowing us to connect with our ancestors, understand our roots, and appreciate the rich tapestry of our cultural diversity. In this ever-changing world, exploring innovative approaches to conserve, digitize, and promote access to these treasures for the benefit of present and future generations is crucial. Libraries must preserve these rare collections, which are essential for future generations. This paper mainly focuses on the important deterioration factors for paper objects and book materials. It provides various methods, tools, and techniques for conserving manuscripts and rare collections in libraries. In conclusion, this study recommends the essential skills and competencies that Library and Information Science (LIS) professionals should possess. These competencies are vital for preserving and restoring manuscripts and rare materials, ensuring their usability for future generations, thus contributing to preserving a nation\u27s cultural heritage

Assessment of Professionals’ Outlook on the Application of Electronic Security Systems in Select University Libraries of Northern India

In a digital era, library professionals are not only responsible for efficient transaction services but also act as custodian of material in all forms. With the constraints of funding, more and more librarians are relying on different technological advances such as Electronic Security Systems (ESSs) to bring security to library material, building, and premises. The present paper uses survey methodology to assess their perception of library professionals of select libraries of Northern India on different ESSs such as Radio Frequency Identification (RFID), Closed-circuit television (CCTV), Biometric and Burglar system and its applications, benefits, and problems. The work highlighted that most of the libraries are using technology such as RFID, or Electro-Magnetic (EM) Tags and surveillance system than Biometric and Burglar for the security of library materials. The study raises awareness of the importance of ESSs for the betterment of the libraries and emphasizes the need to implement such security systems

Altmetric Analysis of Highly Cited Publications on Digital Library in Brazil and India: A Comparative Study

In Library and Information Science, Altmetrics is one of the emerging metrics to capture the online attention of scholarly literature. The present paper is an attempt to do a correlation study of an altmetric score and citations received by the highly cited publications of Digital library in Brazil and India country during 1989-2017. The study reveals that India is the county which received altmetric attention as compared to Brazil. While doing Altmetric analysis, it was found that discipline wise, Librarians followed by PhD scholar are the maximum readers whereas subject-wise, Computer science professionals contribute the maximum readership followed by social science disciplines in India in the field of a digital library. So, it is the need of time to explore the area more so that altmetric would become one of the standard indicators to measure the research impact in a professional

Combining Information from Crosslinks and Monolinks in the Modeling of Protein Structures

Monolinks are produced in a chemical crosslinking mass spectrometry experiment and are more abundant than crosslinks. They convey residue exposure information, but so far have not been used in the modeling of protein structures. Here, we present the Monolink Depth Score (MoDS), for assessing structural models based on the depth of monolinked residues, corresponding to their distance to the nearest bulk water. Using simulated and reprocessed experimental data from the Proteomic Identification Database, we compare the performance of MoDS to MNXL, our previously developed score for assessing models based on crosslinking data. Our results show that MoDS can be used to effectively score models based on monolinks, and that a crosslink/monolink combined score (XLMO) leads to overall higher performance. The work strongly supports the use of monolink data in the context of integrative structure determination. We also present XLM-Tools, a program to assist in this effort, available at: https://github.com/Topf-Lab/XLM-Tools

Methods for Molecular Modelling of Protein Complexes.

Biological processes are often mediated by complexes formed between proteins and various biomolecules. The 3D structures of such protein-biomolecule complexes provide insights into the molecular mechanism of their action. The structure of these complexes can be predicted by various computational methods. Choosing an appropriate method for modelling depends on the category of biomolecule that a protein interacts with and the availability of structural information about the protein and its interacting partner. We intend for the contents of this chapter to serve as a guide as to what software would be the most appropriate for the type of data at hand and the kind of 3D complex structure required. Particularly, we have dealt with protein-small molecule ligand, protein-peptide, protein-protein, and protein-nucleic acid interactions.Most, if not all, model building protocols perform some sampling and scoring. Typically, several alternate conformations and configurations of the interactors are sampled. Each such sample is then scored for optimization. To boost the confidence in these predicted models, their assessment using other independent scoring schemes besides the inbuilt/default ones would prove to be helpful. This chapter also lists such software and serves as a guide to gauge the fidelity of modelled structures of biomolecular complexes

Radiative Transfer for Exoplanet Atmospheres

Remote sensing of the atmospheres of distant worlds motivates a firm understanding of radiative transfer. In this review, we provide a pedagogical cookbook that describes the principal ingredients needed to perform a radiative transfer calculation and predict the spectrum of an exoplanet atmosphere, including solving the radiative transfer equation, calculating opacities (and chemistry), iterating for radiative equilibrium (or not), and adapting the output of the calculations to the astronomical observations. A review of the state of the art is performed, focusing on selected milestone papers. Outstanding issues, including the need to understand aerosols or clouds and elucidating the assumptions and caveats behind inversion methods, are discussed. A checklist is provided to assist referees/reviewers in their scrutiny of works involving radiative transfer. A table summarizing the methodology employed by past studies is provided.Comment: 7 pages, no figures, 1 table. Filled in missing information in references, main text unchange

Atmospheric retrieval of exoplanets

Exoplanetary atmospheric retrieval refers to the inference of atmospheric properties of an exoplanet given an observed spectrum. The atmospheric properties include the chemical compositions, temperature profiles, clouds/hazes, and energy circulation. These properties, in turn, can provide key insights into the atmospheric physicochemical processes of exoplanets as well as their formation mechanisms. Major advancements in atmospheric retrieval have been made in the last decade, thanks to a combination of state-of-the-art spectroscopic observations and advanced atmospheric modeling and statistical inference methods. These developments have already resulted in key constraints on the atmospheric H2O abundances, temperature profiles, and other properties for several exoplanets. Upcoming facilities such as the JWST will further advance this area. The present chapter is a pedagogical review of this exciting frontier of exoplanetary science. The principles of atmospheric retrievals of exoplanets are discussed in detail, including parametric models and statistical inference methods, along with a review of key results in the field. Some of the main challenges in retrievals with current observations are discussed along with new directions and the future landscape

Using Structure to Explore the Sequence Alignment Space of Remote Homologs

Protein structure modeling by homology requires an accurate sequence alignment between the query protein and its structural template. However, sequence alignment methods based on dynamic programming (DP) are typically unable to generate accurate alignments for remote sequence homologs, thus limiting the applicability of modeling methods. A central problem is that the alignment that is “optimal” in terms of the DP score does not necessarily correspond to the alignment that produces the most accurate structural model. That is, the correct alignment based on structural superposition will generally have a lower score than the optimal alignment obtained from sequence. Variations of the DP algorithm have been developed that generate alternative alignments that are “suboptimal” in terms of the DP score, but these still encounter difficulties in detecting the correct structural alignment. We present here a new alternative sequence alignment method that relies heavily on the structure of the template. By initially aligning the query sequence to individual fragments in secondary structure elements and combining high-scoring fragments that pass basic tests for “modelability”, we can generate accurate alignments within a small ensemble. Our results suggest that the set of sequences that can currently be modeled by homology can be greatly extended